MOTS-c Nasal Spray

MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a unique, naturally occurring 16-amino acid peptide encoded within the mitochondrial genome rather than the nuclear DNA. Functioning as a mitochondrial-derived hormone, MOTS-c plays a pivotal role in metabolic homeostasis. It is widely researched for its ability to regulate insulin sensitivity and promote metabolic flexibility, effectively communicating mitochondrial status to the rest of the cell to coordinate energy expenditure.

Our intranasal delivery system is engineered for rapid mucosal absorption, offering an optimized pathway for systemic distribution. This delivery method is particularly advantageous for researchers studying the peptide's effects on systemic metabolism and its potential to cross the blood-brain barrier for neuro-metabolic research.

Key Research Mechanisms:

• AMPK Activation: Potently activates the AMP-activated protein kinase (AMPK) pathway, which serves as the body’s "master metabolic switch" to enhance glucose uptake and fatty acid oxidation.

• Insulin Sensitivity Enhancement: Extensively studied for its ability to reverse age-associated and diet-induced insulin resistance, making it a primary candidate for obesity and type-2 diabetes research models.

• Mitochondrial Biogenesis: Promotes the creation of new mitochondria and improves the efficiency of existing ones, supporting research into physical performance, endurance, and cellular longevity.

• Exercise Mimetic Properties: Demonstrates the ability to mimic the beneficial metabolic effects of physical exercise at the molecular level, even in sedentary research subjects.

Product Specifications:

• Compound: MOTS-c (Mitochondria-derived peptide)

• Presentation: 10MG Lyophilized Powder

• Purity: >99% (HPLC and Mass Spectrometry Verified)

• Format: Intranasal (Includes sterile glass vial and specialized nasal spray applicator)

Note: This kit requires reconstitution with bacteriostatic or sterilized water prior to use.

Research Disclaimer: This highly purified formulation is synthesized strictly for in vitro laboratory research and professional analytical purposes. It is not intended for human consumption, diagnostic, or therapeutic use.

Lyophilized Presentation: Store at room temperature (below 25°C) out of direct sunlight for short-term handling. For long-term preservation, store in a freezer (-20°C).

Post-Reconstitution: Once mixed with bacteriostatic or sterile water, the solution must be refrigerated (2°C to 8°C) and used within 30-45 days to ensure structural stability and peak efficacy.

Every batch is rigorously tested utilizing High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS). We guarantee a purity threshold exceeding 99%, ensuring absolute precision in your research protocols. Certificates of Analysis are available upon request.